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STUDY OF PRODUCTION OF INACTIVATED INFLUENZA VACINE FOR HUMAN ON EGG-GROWN FROM REASSORTANTS NIBRG-14 AT INSTITUE OF VACCINES AND MEDICAL BIOLOGICALS
IVAC has successfully produced 5 lots of absorbed vaccine A/H5N1 (FLUVAC) using NIBRG-14 Strain and embryonated eggs. The immunological response in animals (mice, guinea pig and chicken) has evolved high titer of anti-haemagglutinin (from 40 to >320 HIU) and reached average ratio from 76,6% - 100%. Initially, production and quality control processes have been set up at IVAC.
Le Van Hiep
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